Search on: MESULAM SYNDROME 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Aphasia, Primary Progressive 
Descriptor Spanish:   Afasia Progresiva Primaria 
Descriptor Portuguese:   Afasia Primária Progressiva 
Synonyms English:   Mesulam Syndrome  
Tree Number:   C10.228.140.380.132
C10.597.606.150.500.800.100.155
C23.888.592.604.150.500.800.100.155
F03.615.400.125
Definition English:   A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26) 
Indexing Annotation English:   a clinical entity: do not confuse with descriptions of the progression of aphasia in case reports
History Note English:   1996 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DH diet therapy DT drug therapy
EC economics EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RH rehabilitation
SU surgery TH therapy
US ultrasonography UR urine
VI virology  
Record Number:   32833 
Unique Identifier:   D018888 

Occurrence in VHL:
 

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